Fantasy Football Week 16 RB Rankings presented by Dynasty Vipers

| 1 | Todd Gurley | LAR | @TEN |
| 2 | Le’Veon Bell | PIT | @HOU |
| 3 | Alvin Kamara | NOS | ATL |
| 4 | Ezekiel Elliott | DAL | SEA |
| 5 | LeSean McCoy | BUF | @NEP |
| 6 | DeVonta Freeman | ATL | @NOS |
| 7 | Melvin Gordon | LAC | @NYJ |
| 8 | Mark Ingram | NOS | ATL |
| 9 | Kareem Hunt | KCC | MIA |
| 10 | Christian McCaffery | CAR | TBB |
| 11 | Leonard Fournette | JAC | @SF |
| 12 | Kenyan Drake | MIA | @KCC |
| 13 | Alex Collins | BAL | IND |
| 14 | Dion Lewis | NEP | BUF |
| 15 | Jordan Howard | CHI | CLE |
| 16 | Latavius Murray | MIN | @GBP |
| 17 | Joe Mixon | CIN | DET |
| 18 | Carlos Hyde | SF | JAC |
| 19 | Jerrick McKinnon | MIN | @GBP |
| 20 | Samaje Perine | WSH | DEN |
| 21 | DeMarco Murray | TEN | LAR |
| 22 | Marshawn Lynch | OAK | @PHI |
| 23 | Lamar Miller | HOU | PIT |
| 24 | Isiah Crowell | CLE | @CHI |
| 25 | Duke Johnson | CLE | @CHI |
| 26 | CJ Anderson | DEN | @WSH |
| 27 | Jay Ajayi | PHI | OAK |
| 28 | Kerwynn Williams | ARI | NYG |
| 29 | Peyton Barber | TBB | @CAR |
| 30 | Aaron Jones | GBP | MIN |
| 31 | Jonathan Stewart | CAR | TBB |
| 32 | Jamaal Williams | GBP | MIN |
| 33 | James White | NEP | BUF |
| 34 | Tevin Coleman | ATL | @NOS |
| 35 | Bilal Powell | NYJ | LAC |
| 36 | Derrick Henry | TEN | LAR |
| 37 | Frank Gore | IND | @BAL |
| 38 | Tarik Cohen | CHI | CLE |
| 39 | Wayne Gallman | NYG | @ARI |
| 40 | Mike Davis | SEA | @SEA |
| 41 | Theo Riddick | DET | @CIN |
| 42 | Orleans Darkwa | NYG | @ARI |
| 43 | Gio Bernard | CIN | DET |
| 44 | JD McKissic | SEA | @DAL |
| 45 | Matt Forte | NYJ | LAC |
| 46 | Corey Clement | PHI | OAK |
| 47 | Danny Woodhead | BAL | IND |
| 48 | Alfred Blue | HOU | PIT |
| 49 | Charles Sims | TBB | @CAR |
| 50 | LeGarrette Blount | PHI | OAK |

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