Terrelle Pryor (knee) has been ruled out for Week 11. Pryor practiced on a limited basis Friday and was officially listed as questionable.
Undrafted rookie Matt McGloin took the majority of the first-team reps this week and will make his first NFL start.
McGloin completed 7 of 15 passes (46.7 percent) for 87 yards (5.8 yards per attempt) and a 65.1 passer rating in garbage time in the loss to the Philadelphia Eagles two weeks ago.
He will be in charge come Sunday.